Undoubtedly, CBD or Cannabidiol oil derived from cannabis Sativa plants can cure a bunch of symptoms effectively. Unlike THC, CBD is non-addictive and non-psychoactive that makes it effective in treating various health diseases. 

Furthermore, CBD is widely helpful in treating recurrent seizures, chronic pain, anxiety, depression, schizophrenia, neuropathic pain, Parkinson’s disease, inflammatory bowel disease, and cancer. Even though it offers huge relief from health issues, it interacts with certain medications. 

If you’re worried about the CBD-drug interaction, read the article to find what you shouldn’t take with CBD. 

Which Drugs Should Not Be Taken with CBD? 

Below we have mentioned the list of drugs that can adversely interact with CBD oil and result in serious side effects. Have a look at the list of pharmaceutical prescriptions and medications which you shouldn’t consume with CBD. 

  • Beta-Blockers
  • Benzodiazepines
  • Calcium Channel Blockers
  • Proton-Pump Inhibitors (PPIs)
  • Prokinetics
  • Steroids and Corticosteroids
  • Sulfonylureas
  • Angiotensin II Blockers
  • Antiarrhythmics
  • Antibiotics
  • Antidepressants
  • Anticonvulsants / Anti-Seizure Medications
  • Antihistamines
  • Antipsychotics
  • Anesthetics
  • HIV Antivirals
  • HMG CoA Reductase Inhibitors (Statins)
  • Immune Modulators
  • Non-Steroidal Anti-Inflammatory medicines. 
  • Oral Hypoglycemic Drugs. 

If you are using any of the drugs mentioned above, consult your healthcare professional before using CBD Oil. 

CBD Interaction with Drugs & Medications. 

Now we will discuss the most prescribed drugs that have adverse effects after they come in contact with CBD. 

  • CBD & Ibuprofen Interaction. 

Ibuprofen falls under Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). During inflammation and severe pain, doctors recommend Ibuprofen. Furthermore, various studies are going on to know more about the interactions between CBD and Ibuprofen. According to recent research by health experts, a change in dosage results in CBD exchange with Ibuprofen. If a specific dosage limit is crossed, Ibuprofen and CBD can interact and lead to severe effects on the nervous system. To buy high-quality CBD capsules, you can visit the online store of CBDfx from here  https://cbdfx.com/collections/cbd-hemp-capsules/ and buy them at a single click.

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  • CBD & Lamictal Interaction. 

Lamictal is prescribed to a person suffering from recurrent seizures and epilepsy. When CBD and Lamictal combine, they show side effects such as confusion, drowsiness, dizziness, and complication in focussing. Furthermore, in some cases, it can lead to judgments issues. Various studies have revealed that consuming CBD alone will not cause any side effects. This indicates that Lamictal can severely interact with CBD, causing severe problems in few cases. Usually, the severity of the damage depends on the dosage of medication

  • CBD & Adderall Interaction. 

A stimulant of the central nervous system, Adderall, is used to reduce hyperactivity and improve your attention span. Furthermore, it is effective in treating attention deficit hyperactivity disorder (ADHD) effectively. When Adderall and CBD interact with each other, it leads to a loss in appetite. However, researchers are still searching to find more about this interaction. 

  • CBD & Lisinopril interaction.


When a person needs to lower his blood pressure, doctors recommend adding Lisinopril to their medication list. Both CBD and Lisinopril help lower blood pressure. Consuming both of them simultaneously will result in an excessive lowering of blood pressure which in turn will make you weak and dizzy, so if you are looking to put in CBD with your antihypertensive remedies. 

  • CBD & Thyroid meds interaction. 

Both CBD and Thyroid meds undergo processing by the CYP450 enzyme system. Combining CBD with your prescribed Thyroid meds will result in mild nausea and hyperthyroidism. The reason being the extra thyroxine secreted by consuming both the meds at the same time. Furthermore, the body can’t metabolize the excessive thyroxine secreted during the process, resulting in serious side effects. 

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One key point to remember is that CBD alone does not cause any of the side effects. Consuming it with certain medications can result in few symptoms. Various researchers have proved that CBD is safe to drink. So if you aren’t sure about the side effects of drugs when combined with CBD. Please make sure you consult your doctor and give him knowledge about prescription meds and over-the-counter (OTC) medicines that you are consuming. 

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